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Ssris treat depression by increasing levels of serotonin in the brain. Serotonin is one of the chemical messengers (neurotransmitters) that carry signals between brain nerve cells (neurons). Ssris block the reabsorption (reuptake) of serotonin into neurons. This makes more serotonin available to improve transmission of messages between neurons.   in this installment i will discuss selective serotonin reuptake inhibitors, or ssris. Ssris were developed in the 1970s with the goal of treating depression by increasing serotonin levels. Serotonin is probably the most important neurotransmitter in the brain because it naturally and effectively treats depression, anxiety and insomnia, as well as symptoms such as fatigue, irritability, agitation, anger, aggression, hostility, impulse dyscontrol and a variety of other mood issues.   a selective serotonin reuptake inhibitor, or ssri, is a type of drug that is most commonly used to combat depression and anxiety. Ssri medications you may be familiar with include zoloft (sertraline) prozac (fluoxetine) celexa (citalopram) lexapro (escitalopram) paxil (paroxetine) treating anxiety can be done with or without medication. Neurotransmitter serotonin plays an important role in genesis of emotional and mood disorders. 13 with recent advances in pharmacologic treatment of depression, the serotonin reuptake inhibitors are used in treatment to increase central serotonin levels with subsequent modulation of the pharmacophysiologic state involved in depressive disorders. Antidepressants help by blocking the re-absorption of serotonin where it derived from causing higher levels and ensuring balance between the neurons in the brain with reduced characteristics of depression.

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