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Ssris treat depression by increasing levels of serotonin in the brain. Serotonin is one of the chemical messengers (neurotransmitters) that carry signals between brain nerve cells (neurons). Ssris block the reabsorption (reuptake) of serotonin into neurons. This makes more serotonin available to improve transmission of messages between neurons.   in this installment i will discuss selective serotonin reuptake inhibitors, or ssris. Ssris were developed in the 1970s with the goal of treating depression by increasing serotonin levels. Serotonin is probably the most important neurotransmitter in the brain because it naturally and effectively treats depression, anxiety and insomnia, as well as symptoms such as fatigue, irritability, agitation, anger, aggression, hostility, impulse dyscontrol and a variety of other mood issues. Selective serotonin reuptake inhibitors (ssris) are a widely used type of antidepressant. Theyre mainly prescribed to treat depression, particularly persistent or severe cases, and are often used in combination with a talking therapy such as cognitive behavioural therapy (cbt). Ssris are usually the first choice medication for depression because they generally have fewer side effects than. Despite previous safety concerns, selective serotonin reuptake inhibitors (ssris) remain a key component of the treatment of moderate to severe depression episodes in adolescents. The impact of ssris on the developing adolescent brain, however, remains unclear.

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